5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID
5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
CAS: 128455-63-0
Molecular Formula: C6H4ClF3N2O2
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID - Names and Identifiers
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID - Physico-chemical Properties
| Molecular Formula | C6H4ClF3N2O2 |
| Molar Mass | 228.56 |
| Density | 1.71±0.1 g/cm3(Predicted) |
| Melting Point | 201 °C |
| Boling Point | 284.4±40.0 °C(Predicted) |
| Flash Point | 125.8°C |
| Vapor Presure | 0.0014mmHg at 25°C |
| pKa | 1.77±0.50(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID - Introduction
5-Chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid, also known as CF3-Py-COOH, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-Chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid is a white solid.
-Solubility: It can be dissolved in many organic solvents, such as methanol, ethyl acetate and dichloromethane. However, its solubility in water is relatively low.
Use:
-can be used as pharmaceutical intermediates: 5-chloro -1-methyl -3-trifluoromethyl -1H-pyrazole -4-carboxylic acid can be used as an important intermediate for the synthesis of antiviral, anti-tumor and anti-inflammatory drugs.
-for organic synthesis reaction: it can be used for a variety of reactions in organic synthesis, such as ammoniation reaction, ethanolamine reaction and etherification reaction.
Preparation Method:
-Usually, 5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazole can be obtained by hydrogenation, oxidation, and further esterification of 5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid.
Safety Information:
The specific risk of-5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid has not been clearly reported, but as an organic compound, attention should be paid to its irritation to the skin, eyes and respiratory system.
-During use, appropriate personal protective measures must be taken, such as wearing protective glasses, gloves and protective masks.
-It should be stored in a dark, dry, well-ventilated place, away from fire and combustibles.
Nature:
-Appearance: 5-Chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid is a white solid.
-Solubility: It can be dissolved in many organic solvents, such as methanol, ethyl acetate and dichloromethane. However, its solubility in water is relatively low.
Use:
-can be used as pharmaceutical intermediates: 5-chloro -1-methyl -3-trifluoromethyl -1H-pyrazole -4-carboxylic acid can be used as an important intermediate for the synthesis of antiviral, anti-tumor and anti-inflammatory drugs.
-for organic synthesis reaction: it can be used for a variety of reactions in organic synthesis, such as ammoniation reaction, ethanolamine reaction and etherification reaction.
Preparation Method:
-Usually, 5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazole can be obtained by hydrogenation, oxidation, and further esterification of 5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid.
Safety Information:
The specific risk of-5-chloro-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid has not been clearly reported, but as an organic compound, attention should be paid to its irritation to the skin, eyes and respiratory system.
-During use, appropriate personal protective measures must be taken, such as wearing protective glasses, gloves and protective masks.
-It should be stored in a dark, dry, well-ventilated place, away from fire and combustibles.
Last Update：2024-04-09 02:00:41
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Product Name: 5-Chloro-1-Methyl-3-(Trifluoromethyl)-1H-Pyrazole-4-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 128455-63-0
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 128455-63-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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